VTCN1 / B7H4 Antibody from BIORBYT LTD.
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| Antigenic Specificity | VTCN1 / B7H4 |
| Clone | B7H4/2652R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | Protein A purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | ELISA, FACS, IF, IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
| Immunogen | A recombinant human partial protein was used as the immunogen for this recombinant B7-H4 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q7Z7D3 |
| Catalog # | orb606859 |
| Price | $764 |
| Order / More Info | VTCN1 / B7H4 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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