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Antigenic Specificity | MITF |
Clone | MPAF3-2R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | Protein A purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MITF (microphthalmia transcription factor) is a transcription factor that regulates the expression of genes with essential roles in cell differentiation, proliferation and survival. Binds to symmetrical DNA sequences (E-boxes) (5'-CACGTG-3') found in the promoters of target genes, such as BCL2 and tyrosinase (TYR). Plays an important role in melanocyte development by regulating the expression of tyrosinase (TYR) and tyrosinase-related protein 1 (TYRP1). Plays a critical role in the differentiation of various cell types, such as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium. [UniProt] |
Immunogen | Recombinant full-length human protein was used as the immunogen for the recombinant MITF antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: O75030 |
Catalog # | orb534458 |
Price | $764 |
Order / More Info | MITF Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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