SMDF Antibody from BIORBYT LTD.

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Antigenic SpecificitySMDF
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size100 ul
Concentrationn/a
ApplicationsWB
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DescriptionRabbit polyclonal to SMDF.The neuregulin (also known as heregulin) cytokine family is comprised of four genes that encode anumber of secreted or membrane-bound isoforms. All family members share an EGF-like domain thatinteracts with the ErbB family of tyrosine kinase receptors. The NRG1 gene is the most pleiotropic,encoding more than 14 soluble or transmembrane proteins. NRG1 isoforms can be classified into typeI (neu differentiation factor, NDF; heregulin, HRG; acetylcholine receptor inducing activity, ARIA), typeII (glial growth factor, GGF) and type III (sensory and motor neuron-derived factor, SMDF) isoforms.These isoforms are tissue-specifically expressed and differ significantly in their structures, and theyplay important roles during development of both the nervous system and the heart. Dysregulation ofNRG1 has been linked to diseases such as cancer, schizophrenia and bipolar disorder (BPD).
ImmunogenN-terminal region of human SMDF
Other NamesSMDF,Proneuregulin1,membranebound isoform SMDF; sensory and motor neuron derived factor
Gene, Accession #UniProt: Q02297
Catalog #orb67017
Price$527
Order / More InfoSMDF Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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