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Antigenic Specificity | Neuropilin 1 / NRP1 |
Clone | NRP1/4620 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Neuropilin is a type I transmembrane receptor that has been implicated in aspects of axon growth and guidance and has been shown to act as a high affinity receptor for class III semaphorins and vascular endothelial growth factor (VEGF). A closely related protein, neuropilin-2, shares a common domain structure and signifcant homology with neuropilin and also acts as a receptor for the class III semaphorins and VEGF. Both neuropilins are involved in regulating many physiological pathways including axonal guidance and angiogenesis, however they exhibit differential expression in the adult vasculature. Neuropilin-2 is polysialylated and expressed on the surface of dendritic cells. It is also expressed by venous and lymphatic endothelium. Neuropilin is expressed predominantly by arterial endothelium. |
Immunogen | A recombinant partial protein (within amino acids 700-900) from the human protein was used as the immunogen for the Neuropilin-1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: O14786 |
Catalog # | orb1826347 |
Price | $764 |
Order / More Info | Neuropilin 1 / NRP1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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