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Antigenic Specificity | HSP47 |
Clone | 1C4-1A6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | ATTO-390 conjugate |
Size | 200 ug |
Concentration | 1 mg/ml |
Applications | ICC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to CENP-A Conjuagted to ATTO 390 (ATTO-390). Hsp47 is a chaperone protein, member of the superfamily of serine proteinase inhibitors. Also known as SERPINH1, a serine proteinase inhibitor. It is a stress protein that resides in the endoplasmic reticulum, has an active role on the intracellular process of folding, assembly and secretion of pro-collagens. Recent studies have shown the association of on an increased expression of Hsp47 around fibrotic lesions. The identification of a novel biomarker on cell therapies aimed to reduce the progression of fibrotic diseases, could be used potentially as a universal marker, since Hsp47 binds a single substrate. Type I collagen is fundamental during the healing process after a myocardial infarction. It is critical in the position of collagen-produced cells and the assembly of collagen fibrils.. |
Immunogen | Human HSP47, full length |
Other Names | SerpinH1, Colligin, Gp46, serine proteinase inhibitor, cysteine proteinase inhibitor, collagen binding protein |
Gene, Accession # | Gene ID: 871, UniProt: P50454 |
Catalog # | orb148117 |
Price | $684 |
Order / More Info | HSP47 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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