Macrophage / Histiocytoma Marker Antibody from BIORBYT LTD.

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Antigenic SpecificityMacrophage / Histiocytoma Marker
CloneD11
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG1, kappa
FormatProtein G purified
Size20 ug, 100 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionIn Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this mAb and a standard CD68 mAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This mAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This mAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
ImmunogenA membrane preparation from human hepatocytes was used as the immunogen for the Macrophage / Histiocytoma Marker antibody.
Other Namesn/a
Gene, Accession #n/a
Catalog #orb749974
Price$405
Order / More InfoMacrophage / Histiocytoma Marker Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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Email: info@biorbyt.com
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