B7-H6 / NCR3LG1 Antibody from BIORBYT LTD.

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Antigenic SpecificityB7-H6 / NCR3LG1
CloneB7H6/4821
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionB7-H6 (NCR3LG1) is a transmembrane endogenous ligand expressed on the surfaces of tumor cells. B7-H6 binds with NKp30 present on NK cells. Binding of B7-H6 to NKp30 causes the ligation of NKp30 subsequently inducing NK cell activation and target cell cytolysis. B7-H6 is not constitutively expressed on normal tissue. Whether it can be expressed endogenously under certain conditions is under investigation. B7-H6 has been detected on circulating pro-inflammatory CD14(+)CD16(+) monocytes in some patients with sepsis.
ImmunogenA portion of amino acids 38-169 from the human protein was used as the immunogen for the B7-H6 antibody.
Other Namesn/a
Gene, Accession #UniProt: Q68D85
Catalog #orb699800
Price$764
Order / More InfoB7-H6 / NCR3LG1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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