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Antigenic Specificity | IL18R1 / Interleukin 18 receptor alpha |
Clone | IL18R1/7591 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-Gamma production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1Alpha or IL-1beta. The association of IL-18 to IL-18R leads to activation of NFkB. At present two subunits of IL-18R have been characterized: IL-18RAlpha and IL-18Rbeta. IL-18RAlpha has been described as the ligand-binding chain and IL-18Rbeta as the signal-transduction chain. |
Immunogen | A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IL18R1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q13478 |
Catalog # | orb1823894 |
Price | $764 |
Order / More Info | IL18R1 / Interleukin 18 receptor alpha Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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