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Antigenic Specificity | NME2 / Nucleoside diphosphate kinase B / NDKB |
Clone | NME2/6433 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. |
Immunogen | Recombinant full-length human NME2 protein was used as the immunogen for the NME2 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P22392 |
Catalog # | orb1825035 |
Price | $405 |
Order / More Info | NME2 / Nucleoside diphosphate kinase B / NDKB Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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