CD45RA (Leukocyte marker) Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-CD45RA (Leukocyte marker) antibody, protein, ELISA kits.
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| Antigenic Specificity | CD45RA (Leukocyte marker) |
| Clone | PTPRC/4367R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | unconjugated |
| Size | 100 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD45 is a family of single chain transmembrane glycoproteins, consisting of at least four isoforms which share a common large intracellular domain. Their extracellular domains are rod shaped, heavily glycosylated. The different isoforms are produced by alternative messenger RNA splicing of three exons of a single gene on chromosome 1q31-32.CD45 is exclusively expressed in haematolymphoid cells. Almost all haematolymphoid cells, including precursor cells and mature B- and T-lymphocytes, granulocytes, monocytes/histiocytes and interdigitating reticulum cells and follicular dendritic cells express CD45. This protein is detected in the large majority of haematolymphoid neoplasms, i.e., leukemias and malignant lymphomas. Overall, about 90% of malignant lymphomas are CD45 positive.CD45 is an important marker in the primary tumor screening panel in order to identify haematolymphoid differentiation. Loss of CD45 in precursor B-cell neoplasms is a negative prognostic parameter. |
| Immunogen | A recombinant partial protein sequence (within amino acids 1-600) from the human protein was used as the immunogen for the CD45RA antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P08575 |
| Catalog # | orb1824325 |
| Price | $764 |
| Order / More Info | CD45RA (Leukocyte marker) Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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