IL1RA / Interleukin-1 Receptor Antagonist / IL1RN Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-IL1RA / Interleukin-1 Receptor Antagonist / IL1RN antibody, protein, ELISA kits.
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| Antigenic Specificity | IL1RA / Interleukin-1 Receptor Antagonist / IL1RN |
| Clone | IL1RA/4715 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2, kappa |
| Format | unconjugated |
| Size | 100 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Two forms of interleukin-1, designated IL-1a and IL-1beta, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1a and IL-1beta bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation acting as an activator of T and B lymphocytes and natural killer (NK) cells. IL-1 receptor antagonist (IL-1ra) is a cytokine that inhibits IL-1a and IL-1beta binding to interleukin receptors. By neutralizing the activity of IL-1, IL-1ra contributes to the inhibition of the immune and inflammatory responses and has been targeted as a drug for the treatment of severely active rheumatoid arthritis. There are four isoforms of IL-1ra that are produced as a result of alternative splicing events. |
| Immunogen | A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Interleukin-1 Receptor Antagonist antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P18510 |
| Catalog # | orb1823881 |
| Price | $764 |
| Order / More Info | IL1RA / Interleukin-1 Receptor Antagonist / IL1RN Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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