HCG-beta Antibody from BIORBYT LTD.

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Antigenic SpecificityHCG-beta
CloneHCGb/1996R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG, kappa
FormatProtein A purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionThis antibody reacts with a protein of 22kDa, identified as beta subunit of HCG. It does not cross react with the alpha subunit. HCG is a glycoprotein which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG-beta antibody detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate antibody positivity in 90% and 60% of cases respectively; 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior.
ImmunogenRecombinant protein was used as the immunogen for this recombinant HCG-beta antibody.
Other Namesn/a
Gene, Accession #Gene ID: 1082
Catalog #orb606433
Price$764
Order / More InfoHCG-beta Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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