Beta Catenin Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Beta Catenin antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | Beta Catenin |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | FACS, IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, it is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution throughout the cytoplasm results in a diffuse cytoplasmic pattern. Staining with beta-catenin antibody and E-cadherin antibody helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas. |
| Immunogen | A synthetic peptide from the middle of beta-Catenin / p120 protein was used as the immunogen. |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 1499 |
| Catalog # | orb248319 |
| Price | $764 |
| Order / More Info | Beta Catenin Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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