OPTN Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-OPTN antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | OPTN |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to OPTN. Optineurin (OPTN) plays an important role in the maintenance of the Golgi complex, in membrane trafficking, in exocytosis, through its interaction with myosin VI and Rab8. OPTN links myosin VI to the Golgi complex and plays an important role in Golgi ribbon formation. OPTN negatively regulates the induction of IFNB in response to RNA virus infection. Additionally, OPTN plays a neuroprotective role in the eye and optic nerve. OPTN is also probably part of the TNF-alpha signaling pathway that can shift the equilibrium toward induction of cell death. OPTN may act by regulating membrane trafficking and cellular morphogenesis via a complex that contains Rab8 and hungtingtin (HD), and it also may constitute a cellular target for adenovirus E3 14.7, an inhibitor of TNF-alpha functions, thereby affecting cell death. |
| Immunogen | N-terminal region of human OPTN |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q96CV9 |
| Catalog # | orb107111 |
| Price | $527 |
| Order / More Info | OPTN Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240
info@biorbyt.com
http://www.biorbyt.com
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558
Profile of BIORBYT LTD.
Return to Antibodies