KCTD21 Antibody from BIORBYT LTD.

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Antigenic SpecificityKCTD21
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsWB
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DescriptionProbable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142).
ImmunogenRecombinant protein of human KCTD21
Other NamesKCASH2
Gene, Accession #Gene ID: 283219, UniProt: Q4G0X4
Catalog #orb1731771
Price$345
Order / More InfoKCTD21 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
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