Integrase interactor 1 / INI-1 / SMARCB1 / BAF47 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Integrase interactor 1 / INI-1 / SMARCB1 / BAF47 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Integrase interactor 1 / INI-1 / SMARCB1 / BAF47 |
| Clone | INI1/8935R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | unconjugated |
| Size | 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The INI-1 gene, which encodes a functionally uncharacterized protein component of the hSWI/SNF chromatin remodeling complex, is often mutated or deleted in malignant rhabdoid tumor (MRT). Two isoforms of INI-1, that differ by the variable inclusion of amino acids, potentially are produced by differential RNA splicing. The morphology of MRTs can present challenges in differential diagnosis. The overall survival of MRTs relative to its potential mimics (medulloblastoma, supratentorial primitive neuroectodermal tumors (sPNETs) is quite low, and thus differentiation from these other tumors is desirable. Lack of nuclear labeling by anti-INI-1 is characteristic of MRT. The majority of medulloblastomas and sPNETs are labeled by anti-INI-1. MRTs also originate from the kidney and soft tissues. |
| Immunogen | Recombinant full-length human SMARCB1 protein was used as the immunogen for the SMARCB1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q12824 |
| Catalog # | orb1824012 |
| Price | $405 |
| Order / More Info | Integrase interactor 1 / INI-1 / SMARCB1 / BAF47 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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