ROS1 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-ROS1 antibody, protein, ELISA kits.
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| Antigenic Specificity | ROS1 |
| Clone | ROS1/8268R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | unconjugated |
| Size | 100 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ROS1, an orphan receptor tyrosine kinase of the insulin receptor family, was initially identified as a homolog of v-ros from the UR2 sarcoma virus. ROS1 consists of a large extracellular domain that is composed of six fibronectin repeats, a transmembrane domain, and an intracellular kinase domain. While the function of ROS1 is undefined, it has been shown to play an important role in differentiation of epididymal epithelium. The first oncogenic fusion of ROS1, FIG-ROS1, was initially identified by research studies in glioblastoma. Investigators have found additional oncogenic ROS1 fusion proteins in NSCLC (at a frequency of ~1.6%), where the ROS1 kinase domain is fused to the amino-terminal region of a number of different proteins, including CD74 and SLC34A2. |
| Immunogen | A recombinant fragment corresponding to the cytoplasmic domain of human ROS1 protein was used as the immunogen for the ROS1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P08922 |
| Catalog # | orb1823069 |
| Price | $764 |
| Order / More Info | ROS1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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