CD89 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-CD89 antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | CD89 |
| Clone | A59 |
| Host Species | n/a |
| Reactive Species | human, primate |
| Isotype | IgG1 kappa |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | FC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble CD89 is detectable in serum and retains its IgA binding capacity. For signal transduction the association with FcR gamma chain homodimers is needed. CD89 is expressed on granulocytes, monocytes, macrophages, dendritic cells and myeloid cell lines. Its expression is upregulated in presence of IgA immune complexes, stimulators (such as LPS, PMA), TNF alpha, IL1 beta or GM-CSF, and it is downregulated in presence of TGF beta and suramin. Binding of IgA-opsonized targets to CD89 leads to phagocytic and cytotoxic processes of the immunologic defense. |
| Immunogen | Ag8.653 myeloma cells |
| Other Names | FcalphaRI, FcAR, CTB-61M7.2 |
| Gene, Accession # | Gene ID: 2204, UniProt: P24071 |
| Catalog # | orb1881242 |
| Price | $439 |
| Order / More Info | CD89 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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