NEDD4 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | NEDD4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to NEDD4.Neural precursor cell expressed developmentally down-regulated protein 4 (NEDD4) is an E3ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form ofa thioester and then directly transfers the ubiquitin to targeted substrates. NEDD4 is also involved inthe pathway leading to the degradation of VEGFR-2/KDFR independent of its ubiquitin-ligase activity.NEDD4 can monoubiquitinates IGF1R at multiple sites, thus leading to receptor internalization anddegradation in lysosomes. In addition, NEDD4 is part of a signaling complex composed of NEDD4,RAP2A and TNIK, which regulates neuronal dendrite extension and arborization during development. |
| Immunogen | middle region of human NEDD4 |
| Other Names | NEDD4,E3 ubiquitinprotein ligase NEDD4,Cell proliferationinducing gene 53 protein,Neural precursor cellexpressed developmentally downregulated protein 4,NEDD4,KIAA0093,NEDD41 |
| Gene, Accession # | UniProt: P46934 |
| Catalog # | orb67227 |
| Price | $527 |
| Order / More Info | NEDD4 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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