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Antigenic Specificity | Cleaved-Caspase 6 p18 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | ELISA, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A. |
Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179 |
Other Names | CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2 |
Gene, Accession # | Gene ID: 839, UniProt: P55212 |
Catalog # | orb1730715 |
Price | $296 |
Order / More Info | Cleaved-Caspase 6 p18 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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