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Antigenic Specificity | Bax |
Clone | 2A3 |
Host Species | Mouse |
Reactive Species | human, monkey |
Isotype | IgG2a |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis. |
Immunogen | Purified recombinant human Bax protein fragments expressed in E.coli |
Other Names | Apoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4 |
Gene, Accession # | Gene ID: 581, UniProt: Q07812 |
Catalog # | orb1732754 |
Price | $345 |
Order / More Info | Bax Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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