Bax Antibody from BIORBYT LTD.

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Antigenic SpecificityBax
Clone2A3
Host SpeciesMouse
Reactive Specieshuman, monkey
IsotypeIgG2a
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsWB
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DescriptionBax is a key component for cellular induced apoptosis through mitochondrial stress. Upon apoptotic stimulation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Through interactions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability, which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of the caspase activation pathway for apoptosis.
ImmunogenPurified recombinant human Bax protein fragments expressed in E.coli
Other NamesApoptosis regulator BAX; BAX; Bcl-2-like protein 4; BCL2-associated X protein; Bcl2-L-4; BCL2L4
Gene, Accession #Gene ID: 581, UniProt: Q07812
Catalog #orb1732754
Price$345
Order / More InfoBax Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558


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