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Antigenic Specificity | Phospho-BRAF (Thr401) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations. |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Thr401 of human B Raf |
Other Names | BRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1 |
Gene, Accession # | Gene ID: 673, UniProt: P15056 |
Catalog # | orb1733126 |
Price | $345 |
Order / More Info | Phospho-BRAF (Thr401) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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