SHANK2 Antibody from BIORBYT LTD.

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Antigenic SpecificitySHANK2
CloneN23b/6 (Formerly sold as S23b-6)
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
FormatATTO-594 conjugate
Size100 ug
Concentration1 mg/ml
ApplicationsAM, ICC, IHC, IP, WB
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DescriptionMouse monoclonal to SHANK2 (ATTO-594). Shank proteins make up a family of scaffold proteins identified through their interaction with a variety of membrane and cytoplasmic proteins. Shank proteins at postsynaptic sites of excitatory synapses play roles in signal transmission into the postsynaptic neuron. Studies suggest that Shank2 is expressed in the neurons of the developing retina, and could play a role in the neuronal differentiation of the developing retina. Other recent studies suggest that the disruption of glutamate receptors at the Shank postsynaptic platform could contribute to the destruction of the postsynaptic density, which underlies the synaptic dysfunction and loss in Alzheimers disease..
ImmunogenFusion protein amino acids 84-309 (SH3/PDZ domains) of rat Shank2 (SH3 and multiple ankyrin repeat domains protein 2)
Other NamesShank2, PROSAP1, cortactin binding protein 1, KIAA1022, AUTS17, CortBP1, Proline-rich synapse-associated protein 1, SH3 and multiple ankyrin repeat domains protein 2, Cortactin-binding protein 1, proline-rich synapse associated protein 1, SPANK-3, GKAP/SAPAP interacting protein, SHANK, cortactin SH3 domain-binding protein, ProSAP1, CORTBP1CTTNBP1, SH3 and multiple ankyrin repeat domains 2
Gene, Accession #Gene ID: 171093, UniProt: Q9QX74
Catalog #orb148596
Price$573
Order / More InfoSHANK2 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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Email: info@biorbyt.com
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