Edit |   |
---|---|
Antigenic Specificity | NHERF1 |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 200 ul, 100 ul, 50 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal antibody to NHERF1. NHERF1 is a sodium/hydrogen exchanger regulatory cofactor. It interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. NHERF1 also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. It localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in NHERF1 result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this protein is implicated in breast cancer. |
Immunogen | Recombinant fusion protein of human SLC9A3R1(NP_004243.1). |
Other Names | EBP50, NHERF, NHERF-1, NHERF1, NPHLOP2, Regulatory cofactor of Na(+)/H(+) exchanger, Sodium-hydrogen exchanger regulatory factor 1, Solute carrier family 9 isoform A3 regulatory factor 1 |
Gene, Accession # | UniProt: O14745 |
Catalog # | orb154204 |
Price | $490 |
Order / More Info | NHERF1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558