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Antigenic Specificity | Surfactant protein D / SFTPD |
Clone | rSFTPD/8064 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Pulmonary surfactant is primarily responsible for lowering the surface tension at the air-liquid interface in the alveoli, a process that is essential for normal respiration. Pulmonary surfactant is a mixture of phospholipids and proteins, including four distinct surfactant-associated proteins (SPs), SP-A, SP-B, SP-C, SP-D. SP-B and SP-C are predominantly hydrophobic proteins that associate with lipids to promote the absorption of surfactant phospholipids and to reduce the surface tension in the alveoli. SP-A and SP-D are large multimeric proteins belonging to the family of calcium-dependent lectins, designated Collectins, which contribute to the innate immune system. Both SP-A and SP-D have been shown to protect against microbial challenge through binding to the lipid components of the bacterial cell wall and facilitating the rapid removal of microbials. |
Immunogen | A recombinant partial protein (within amino acids 200-375) from the human protein was used as the immunogen for the Surfactant protein D antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P35247 |
Catalog # | orb1826272 |
Price | $764 |
Order / More Info | Surfactant protein D / SFTPD Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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