NME1 / NM23 Antibody from BIORBYT LTD.

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Antigenic SpecificityNME1 / NM23
CloneCPTC-NME1-2
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, kappa
FormatProtein G purified
Size20 ug, 100 ug
Concentrationn/a
ApplicationsWB
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DescriptionThe nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP-K). In humans, NDP kinase A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human C-Myc promotor.
ImmunogenA recombinant full-length human NME1 protein was used as the immunogen for this NME1 antibody.
Other Namesn/a
Gene, Accession #UniProt: P15531
Catalog #orb639833
Price$405
Order / More InfoNME1 / NM23 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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