Edit |   |
---|---|
Antigenic Specificity | CD49f |
Clone | GoH3 |
Host Species | n/a |
Reactive Species | bovine, canine, equine, feline, human, mouse, porcine, primate, rabbit, sheep |
Isotype | IgG2a |
Format | allophycocyanin (APC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD49f (alpha 6 integrin) is a type I transmembrane glycoprotein, which noncovalently associates with CD29 (beta 1 integrin) to form VLA-6, and with CD104 (beta 4 integrin) to form alpha6/beta4 integrin complex. CD49f is expressed on platelets, megakaryocytes, monocytes, T cells and thymocytes. It is widely expressed on many cultured adherent cell lines and on epithelia in non-lymphoid tissues. It is important for adhesion to laminins, invasin, and merosin, hence also for cell migration, embryogenesis, metastasis, formation of hemidesmosomes in epithelia, and other processes. |
Immunogen | mouse mammary tumor cells |
Other Names | ITGA6, VLA6alpha, platelet gpIc, integrin subunit alpha 6 |
Gene, Accession # | Gene ID: 3655, UniProt: P23229 |
Catalog # | orb1806413 |
Price | $439 |
Order / More Info | CD49f Antibody from BIORBYT LTD. |
Product Specific References | n/a |
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558