SHP-1 / PTPN6 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-SHP-1 / PTPN6 antibody, protein, ELISA kits.
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| Antigenic Specificity | SHP-1 / PTPN6 |
| Clone | PTPN6/7543 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PTPN6, which is also designated as SHP-1, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating intracellular signaling for various molecules. In T-cell lymphomas and other malignancies, SHP-1 phosphatase expression is lost, by a thus far undetermined mechanism. Preliminary studies suggest that it may be helpful in differentiating mantle/marginal zone lymphomas (SHP-1+) from follicular lymphomas (SHP-1 negative). |
| Immunogen | A recombinant partial protein sequence (within amino acids 395-595) from the human protein was used as the immunogen for the PTPN6 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P29350 |
| Catalog # | orb1825824 |
| Price | $405 |
| Order / More Info | SHP-1 / PTPN6 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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