Prohibitin / PHB Antibody from BIORBYT LTD.

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Antigenic SpecificityProhibitin / PHB
ClonePHB/3229
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P, WB
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DescriptionThis antibody recognizes a protein of 30kDa which is identified as Prohibitin (PHB), an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although PHB mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. It is an ideal mitochondrial marker. It shows anti-proliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression.
ImmunogenA recombinant human partial protein corresponding to amino acids 167-261 was used as the immunogen for the PHB antibody.
Other Namesn/a
Gene, Accession #UniProt: P35232
Catalog #orb607189
Price$764
Order / More InfoProhibitin / PHB Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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