Beta-Parvin Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Beta-Parvin antibody, protein, ELISA kits.
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| Antigenic Specificity | Beta-Parvin |
| Clone | PARVB/8214R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG, kappa |
| Format | unconjugated |
| Size | 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Beta-parvin, also known as affixin, is a focal adhesion protein belonging to a family of ILKbinding proteins that contain tandem calponin homolog domains. Along with Alpha-parvin, Beta-parvin is one of the most widely researched and characterized members of this family. These two proteins interact with the ILK kinase domain in a way that is mutually exclusive and regulates both the activity of the kinase and actin cytoskeleton adhesion. Studies have shown Beta-parvin to be downregulated within human breast cancer cells, and that its expression may influence the progression of breast cancer (Johnstone, 2008). Additional research indicates a critical role for Beta-parvin in the regulation of cardiac contractility when it is in complex with ILK (Hannigan, 2007). |
| Immunogen | The N-terminal region (residues 1-91) of the human protein was used as the immunogen for the Beta-Parvin antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q9HBI1 |
| Catalog # | orb1824006 |
| Price | $405 |
| Order / More Info | Beta-Parvin Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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