Phospho-BRAF (Thr401) Antibody from BIORBYT LTD.

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Antigenic SpecificityPhospho-BRAF (Thr401)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatunconjugated
Size100 ul
Concentrationn/a
ApplicationsICC, IP, WB
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DescriptionInvolved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations.
ImmunogenA synthesized peptide derived from human Phospho-B Raf (T401)
Other NamesBRAF; BRAF1; RAFB1; Serine/threonine-protein kinase B-raf; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1
Gene, Accession #Gene ID: 673, UniProt: P15056
Catalog #orb1730673
Price$296
Order / More InfoPhospho-BRAF (Thr401) Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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F: +44(0)1223 280 240

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