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Antigenic Specificity | CD45RA (Leukocyte marker) |
Clone | K4B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | Protein G purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | FACS, IF, IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a protein of 205kDa-220kDa, identified as CD45RA. CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve). |
Immunogen | Stimulated human leukocytes were used as the immunogen for the CD45RA antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P08575 |
Catalog # | orb639890 |
Price | $405 |
Order / More Info | CD45RA (Leukocyte marker) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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