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Antigenic Specificity | Integrin alpha E / CD103 |
Clone | rITGAE/2063 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This MAb recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL). |
Immunogen | Recombinant human ITGAE partial protein was used as the immunogen for the recombinant ITGAE antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P38570 |
Catalog # | orb699546 |
Price | $405 |
Order / More Info | Integrin alpha E / CD103 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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