Integrin alpha E / CD103 Antibody from BIORBYT LTD.

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Antigenic SpecificityIntegrin alpha E / CD103
ClonerITGAE/2063
Host SpeciesRecombinant Mouse
Reactive Specieshuman
IsotypeIgG1, kappa
FormatProtein G purified
Size20 ug, 100 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionThis MAb recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).
ImmunogenRecombinant human ITGAE partial protein was used as the immunogen for the recombinant ITGAE antibody.
Other Namesn/a
Gene, Accession #UniProt: P38570
Catalog #orb699546
Price$405
Order / More InfoIntegrin alpha E / CD103 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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