TRIF Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-TRIF antibody, protein, ELISA kits.
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| Antigenic Specificity | TRIF |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of proinflammatory cytokines . |
| Immunogen | Recombinant protein of human TRIF |
| Other Names | TRIF; IIAE6; MyD88-3; PRVTIRB; TICAM-1 |
| Gene, Accession # | Gene ID: 148022, UniProt: Q8IUC6 |
| Catalog # | orb1731247 |
| Price | $345 |
| Order / More Info | TRIF Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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