PDCD1 / PD-1 / PD1 Antibody from BIORBYT LTD.

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Antigenic SpecificityPDCD1 / PD-1 / PD1
ClonePDCD1/4231R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG, kappa
Formatunconjugated
Size100 ug
Concentrationn/a
ApplicationsELISA, IHC-P
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DescriptionPDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
ImmunogenA recombinant fragment corresponding to the extracellular domain of human PDCD1 protein was used as the immunogen for the PDCD1 antibody.
Other Namesn/a
Gene, Accession #UniProt: Q15116
Catalog #orb1823710
Price$764
Order / More InfoPDCD1 / PD-1 / PD1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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