MLK1 Antibody from BIORBYT LTD.

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Antigenic SpecificityMLK1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formataffinity purified
Size100 ul
Concentrationn/a
ApplicationsWB
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DescriptionRabbit polyclonal to MLK1.Mixed lineage kinase 1 (MLK1) is also known as Mitogen-activated protein kinase kinase kinase 9(MAP3K9), which is a serine/threonine kinase acting as an essential component of the MAP kinasesignal transduction pathway. MLK1 plays an important role in the cascades of cellular responsesevoked by changes in the environment. Once activated, MLK1 acts as an upstream activator of theMKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 andMAP2K7/MKK7, which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stressresponse via activator protein-1 (JUN) and GATA4 transcription factors. MLK1 also plays a role inmitochondrial apoptosis signaling pathway, including the release cytochrome c.
Immunogenmiddle region of human MLK1
Other NamesMLK1,Mitogenactivated protein kinase kinase kinase 9,Mixed lineage kinase 1,PRKE1,MAP3K9
Gene, Accession #UniProt: P80192
Catalog #orb67265
Price$462
Order / More InfoMLK1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

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St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558


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