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Antigenic Specificity | ATG4B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 25 ug, 100 ug |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The `autophagy-related gene' ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation. |
Immunogen | A recombinant protein fragment from the N-terminal region of ATG4B was used as the immunogen for this antibody. |
Other Names | n/a |
Gene, Accession # | Gene ID: 23192 |
Catalog # | orb248172 |
Price | $390 |
Order / More Info | ATG4B Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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