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Antigenic Specificity | Bcl-2 |
Clone | ARBC2-1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bcl2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release. [UniProt] |
Immunogen | Recombinant full-length human protein was used as the immunogen for the Bcl2 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P10415 |
Catalog # | orb750150 |
Price | $405 |
Order / More Info | Bcl-2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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