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Antigenic Specificity | CD3 epsilon |
Clone | OKT3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, Functional Studies, ICC, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. It is found on all mature T-lymphocytes, NK, T-cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. It is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. This MAb has been reported to have potent immunosuppressive properties in vivo and has been proven effective in the treatment of renal, heart and liver allograft rejection. |
Immunogen | Human PBMC were used as the immunogen for the CD3e antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P07766 |
Catalog # | orb640029 |
Price | $764 |
Order / More Info | CD3 epsilon Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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