p63 / Tumor protein 63 Antibody from BIORBYT LTD.
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| Antigenic Specificity | p63 / Tumor protein 63 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 20 ug, 100 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts. |
| Immunogen | Recombinant partial human p63 protein was used as the immunogen for this p63 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q9H3D4 |
| Catalog # | orb386105 |
| Price | $405 |
| Order / More Info | p63 / Tumor protein 63 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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