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Antigenic Specificity | ARID1A |
Clone | ARID1A/7735 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2a) and Brg-1 (also designated SNF2b) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits, such as BAF250a (p270 or ARID1A) and BAF250b (ARID1B), are thought to play regulatory roles. |
Immunogen | A recombinant partial protein sequence (within amino acids 1900-2000) from the human protein was used as the immunogen for the ARID1A antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: O14497 |
Catalog # | orb1824529 |
Price | $764 |
Order / More Info | ARID1A Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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