NEDD8 Activating Enzyme E1C Antibody from BIORBYT LTD.
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| Antigenic Specificity | NEDD8 Activating Enzyme E1C |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Immunogen | A synthetic peptide of human UBA3 |
| Other Names | NAE2; UBE1C; hUBA3 |
| Gene, Accession # | Gene ID: 9039, UniProt: Q8TBC4 |
| Catalog # | orb1730749 |
| Price | $345 |
| Order / More Info | NEDD8 Activating Enzyme E1C Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
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