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Antigenic Specificity | CXCR5 / BLR1 / MDR15 |
Clone | CXCR5/8146R |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Burkitt s lymphoma receptor 1 (Blr1), also called CD185, CXCR5 and MDR15, is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemoattractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer s patch follicles. BLC expression in Peyer s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation. |
Immunogen | A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the CXCR5 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P32302 |
Catalog # | orb1825938 |
Price | $405 |
Order / More Info | CXCR5 / BLR1 / MDR15 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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