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Antigenic Specificity | CD3 epsilon |
Clone | rC3e/6966 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the epsilon-chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. |
Immunogen | A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the CD3 epsilon antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P07766 |
Catalog # | orb1825953 |
Price | $405 |
Order / More Info | CD3 epsilon Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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