Cyclin D1 / CCND1 Antibody from BIORBYT LTD.

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Antigenic SpecificityCyclin D1 / CCND1
CloneDCS-6
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2a, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsFACS, IF, IHC-P, WB
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DescriptionThis antibody recognizes a protein of 36kDa, identified as Cyclin D1. It is a putative proto-oncogene overexpressed in a wide variety of human neoplasms and a key cell cycle regulator. This antibody neutralizes the activity of Cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression. Cyclin D1 antibody is useful in identifying mantle cell lymphomas, which stain positive, from CLL/SLL and follicular lymphomas, which stain negative. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
ImmunogenHuman recombinant full length protein was used as the immunogen for this Cyclin D1 antibody.
Other Namesn/a
Gene, Accession #Gene ID: 595
Catalog #orb248183
Price$764
Order / More InfoCyclin D1 / CCND1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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Email: info@biorbyt.com
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