GATA3 Antibody from BIORBYT LTD.

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Antigenic SpecificityGATA3
CloneGATA3/7685R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG, kappa
Formatunconjugated
Size20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionGATA-3 (GATA binding protein 3) is a member of the GATA family of transcription factors. This 50kDa nuclear protein regulates the development and subsequent maintenance of a variety of human tissues, including hematopoietic cells, skin, kidney, mammary gland, and the central nervous system. Among several other roles, GATA-3 involved in luminal cell differentiation in the mammary gland and appears to control a set of genes involved in the differentiation and proliferation of breast cancer. The expression of GATA-3 is associated with the expression of estrogen receptor-alpha (ER) in breast cancer. GATA-3 has been shown to be a novel marker for bladder cancer. The study demonstrated that GATA-3 stained 67% of urothelial Carcinomas, but none of prostate or renal carcinomas.
ImmunogenA recombinant partial protein (within amino acids 150-250) from the human protein was used as the immunogen for the GATA-3 antibody.
Other Namesn/a
Gene, Accession #UniProt: P23771
Catalog #orb1826319
Price$405
Order / More InfoGATA3 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

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Email: info@biorbyt.com
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