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Antigenic Specificity | TFAP2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | 100 µg/ml BSA |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to TFAP2B. Transcription factor AP-2-beta (TFAP2B) belongs to the AP-2 family and is a sequence-specific DNAbinding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5-GCCNNNGGC-3 and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia. |
Immunogen | N-terminal region of human TFAP2B |
Other Names | Transcription factor AP-2-beta, AP2-beta, Activating enhancer-binding protein 2-beta |
Gene, Accession # | UniProt: Q92481 |
Catalog # | orb131791 |
Price | $527 |
Order / More Info | TFAP2B Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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