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Antigenic Specificity | PRKCA / PKC alpha |
Clone | 133 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Protein Kinase C alpha (PKC) is involved in the regulation of cell proliferation during cell cycle progression. This is a calcium-activated, phospholipid-dependent, serine- and threonine-specific enzyme. May play a role in cell motility by phosphorylating CSPG4. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Clone 133 recognizes the isoform of PKC and binds to a sequence at the C terminus of PKC to detect its expression in vitro. |
Immunogen | Full-length protein was used as the immunogen for the PRKCA antibody. The epitope has been mapped to amino acids PQFVHPILQSAV at the C terminus. |
Other Names | n/a |
Gene, Accession # | UniProt: P17252 |
Catalog # | orb699753 |
Price | $764 |
Order / More Info | PRKCA / PKC alpha Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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