CD32 / FCGR2A Antibody from BIORBYT LTD.
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| Antigenic Specificity | CD32 / FCGR2A |
| Clone | FCGR2A/479 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | FACS |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CD32 antibody binds most strongly to the IIa isoforms of CD32 (FcRII), a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes. |
| Immunogen | Recombinant human protein was used as the immunogen for the CD32 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P12318 |
| Catalog # | orb639654 |
| Price | $764 |
| Order / More Info | CD32 / FCGR2A Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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