KDM1A Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | KDM1A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to KDM1A.Lysine-specific histone demethylase 1A (KDM1A) is a histone demethylase that demethylates both'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or acorepressor, depending on the context. KDM1A acts as a corepressor by mediating demethylation ofH3K4me, a specific tag for epigenetic transcriptional activation. KDM1A can demethylate both mono-(H3K4me1) and di-methylated (H3K4me2) H3K4me, and may play a role in the repression of neuronalgenes. KDM1A also acts as a coactivator of androgen receptor (ANDR)-dependent transcription, bybeing recruited to ANDR target genes and mediating demethylation of H3K9me, a specific tag forepigenetic transcriptional repression. KDM1A is required for gastrulation during embryogenesis. |
| Immunogen | middle region of human KDM1A |
| Other Names | KDM1A,Lysinespecific histone demethylase 1A,BRAF35HDAC complex protein BHC110,Flavincontainingamine oxidase domaincontaining protein 2,AOF2,KDM1,KIAA0601,LSD1 |
| Gene, Accession # | UniProt: O60341 |
| Catalog # | orb66998 |
| Price | $527 |
| Order / More Info | KDM1A Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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